Microcrystalline Cellulose and Carboxymethylcellulose Sodium 
 
Liquid dosage forms are a common and popular approach to overcoming the many obstacles of administering medicines to children, the elderly, and animals. However, instabilities such as sedimentation, flocculation, or caking – especially in suspensions – are major challenges in the development of new formulations. VIVAPUR® MCG addresses those challenges and allows a custom balance of rheological properties to guarantee high content uniformity and excellent long-term stability in suspensions, without the need for an excessive increase in viscosity.
 
VIVAPUR® MCG is a synergistic, co-processed composite consisting of microcrystalline cellulose (MCC) and sodium carboxymethylcellulose (Na-CMC). It is a unique suspending and emulsifying agent, which facilitates a wide range of liquid dosage forms. Due to its extraordinary stabilizing mechanism, VIVAPUR® MCG can be used with a broad variety of active pharmaceutical ingredients (APIs), offering the opportunity for new applications and line extensions for existing products.
 
WHAT IS  VIVAPUR® MCG?
VIVAPUR® MCG is a free-flowing powder consisting of microcrystalline cellulose (MCC) and sodium carboxymethyl cellulose (Na-CMC). It is more than just a physical blend; the Na-CMC is interwoven with the microcrystalline cellulose, resulting in unique synergistic properties. The Na-CMC acts as a protective colloid to prevent the re-aggregation of the microcrystalline cellulose and ensures easy dispersibility.
 
APPLICATIONS
VIVAPUR® MCG can be used with a variety of active pharmaceutical ingredients (APIs), offering the opportunity for new applications and line extensions for existing products.  VIVAPUR® MCG is used as a suspending agent, emulsifier, opacifier, and thickener for:
Oral suspensions
Veterinary drenches
Sprays (nasal, oral, or topical sprays)
Reconstitutable powders
Creams, gels, and lotions
 
BENEFITS
Convenience 
Easy handling of the dry powder
Excellent flow
Long shelf-life stability
Hassle-free handling of the activated gel
Easy cleaning of the equipment
Ideal pumpability
Full functionality in hot and cold water
Robust versatile stabilizer
Stable over a wide pH range
Sterilizable and freeze / thaw stable
Compatible with a wide range of ingredients
Combinable and synergistic with other stabilizers
 
High Acceptance
Negligible caloric value
Excellent sensory properties
Odorless & tasteless
Smooth texture
Easy to swallow
Not sticky
Non-laxative
Accurate Dosage
Ideal sprayability
Easy pumpability
Drop-by-drop dosing